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Australian Government: National Measurement InstituteAustralian Government: National Measurement Institute
National Measurement Institute
      

Indicative Project

Detection of ethyl glucuronide and ethylsulfate as indicators of alcohol abuse

Background Info

​The ASDTL is the only laboratory in the Oceania region accredited by the World Anti-Doping Agency (WADA) to carry out doping control analysis in human sport and as such performs virtually all of the sports drug testing carried out in Australia and New Zealand. ASDTL complies with the requirements of ISO/IEC 17025:2005 and is accredited by NATA. Drug testing is not just carried out at major sporting events but is a year round activity with the analysis of some 8000 samples per year from a range of
amateur and professional sports.

Our research program aims to improve analytical techniques used in our laboratory and to investigate new forms of doping which are currently undetectable. We receive funding from the WADA, the
Department of Health, International Olympic Committee and USPartnership for Clean Competition.

Project Description

​This project aims to develop and fully validate methods for ethyl glucuronide and ethylsulfate for estimation of concentration in line with new requirements for the WADA Endogenous Anabolic
Androgenic Steroids Technical Document.

The testosterone to epitestosterone ratio (T/E) can be elevated by the effects of alcohol use. Currently elevated T/E ratios are investigated by isotope ratio mass spectrometry, where the result is negative it is not known whether the T/E ratio may have been influenced by alcohol consumption. WADA wish to ensure that any such affected T/E ratios are not included in an athlete’s profiling data and thus are now proposing measurement of the alcohol metabolites for all elevated T/E ratios.

Examples of Relevant Sudent Courses

Analytical Chemistry, Biochemistry, Chemistry, Measurement Uncertainty, Quality Management, Statistics

Student Level

Honours, Masters

Duration

1 year

Location

North Ryde (NSW)

Section

Australian Sports Drug Testing Laboratory

Contact

Catrin Goebel

Email Contact

catrin.goebel@measurement.gov.au

Interested in this project?

Application Form